Several procedures for non-linear static and dynamic analysis of structures have been developed in recent years. In this paper, the response spectrum analysis is performed on two different shapes i.e. regular and irregular shape of structure by using STAAD PRO. And the comparison results are studied and compared accounting for the earthquake characteristics and the structure dynamic characteristics. As the results show that the earthquake response peak values and the main response frequencies are very close and comparable. It can be referred to by the engineering applications.