Pit-and-fissure sealants of the occlusal surfaces for the posterior teeth are well susceptible to develop dental caries compared to the smooth surfaces due to its complex morphology, which makes dental hygiene a challenging fact which give rise to increased plaque accumulation. The use of pit-and-fissure sealants is to provide inhibition toward microorganisms and aggregation of food particles, thereby inhibiting caries initiating and preventing caries progression. The study aimed to assess the effect of pit-and-fissure sealants postbrushing simulation through photography. For this photogenic original study, eight teeth were selected, with two groups each and four teeth present in each of the groups. Brushing simulator machines are well-established methods for analyzing the efficacy of toothbrushes. A total of 10,000 cycles were accounted for by the machine with linear X-axis and Y-axis = 2500 in each group. The clockwise and counterclockwise = 2500 in each group. From the research, it can be concluded that Group A is found to be more effective than Group B, where Group A is Clinpro sealant and Group B is YuSeal. This pit-and-fissure sealant application is very important in clinical practice to prevent the tooth from getting decayed. This research helps us to establish the amount of reduction in both the groups of sealants postbrushing as various brushing patterns influence the retention of pit-and-fissure sealants.