Peptic ulcer is a common disease of the Gastro Intestinal tract. Contrary to popular belief, ulcer is not caused by spicy food but instead is most commonly due to either an infection or long term use of medications. Standard treatment is a combination of d rugs including antibiotics and a proton pump inhibitors. However, many studies revealed that herbal medicines can effectively treat Peptic ulcer in humans and various animal models. In this review, attempts have been made to know about some plants which may be used in treatment or prevention of peptic ulcers. Utilising herbal medicines could be a valuable alternative to treat Pe ptic ulcer with fewer adverse effects.