A direct
introduction of vinyl ethers into C–H bond of heterocycles
is reported. For this purpose, decarboxylative direct C–H cross-coupling
of 1,3-diazoles with α-carboxyvinyl ethers as coupling partners
was achieved under Pd(0)/Cu(I) cooperative catalysis to produce various
α-heteroarylated vinylethers. This methodology was applied to
the innovative production of heteroarylated enolizable ketones and
naturally occurring bis-oxa(thia)zoles.
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