LGBT has been prohibited in Malaysia and been stated by Prime Minister of Malaysia on 21st September 2018. It becomes one of the top concerns news in Malaysia that faced legal and social challenges from the political aspect and society. The news of the LGBT issues had been published to the public, especially on news portal media. This research aims to determine the concerns of journalists in the process of interpreting LGBT news by using news portal media in Malaysia. At the same time, this research also aims to identify the process of journalists to frame the LGBT news by using the frame-building process affected by internal and external factors. In order to meet objectives, the researcher will analyses the effect of the factors on the news framing of LGBT issues through news portal media in the perceptive of journalism. Framing theory is the main theory that will be used in this research. The researcher will adapt and adopt the framing theory of De Vreese (2005), mainly focus on the frame-building process. At the same time, the researcher will examine the most significant internal and external factors found in the frame-building process which mainly affected in the process of interpreting LGBT issues on news portal media in Malaysia. For the data analysis and findings of this research, the researcher will use content analysis to show out the results by using the codebook. Online news articles about LGBT issues on news portal media of Malaysia such as Malaysiakini and The Star will be filtered and coded in the codebook. This research has delivered valuable insights into the field of journalism in framing different aspects of news.