No abstract

No abstract

No abstract

Mirabimide E, an Unusual N-Acylpyrrolinone from the Blue-Green Alga Scytonema mirabile: Structure Determination and Synthesis. -The title compound (I) is synthesized in order to determine its absolute configuration. Preliminary investigations of (I) reveal antitumor activity. -(PAIK, S.; CARMELI, S.; CULLINGHAM, J.; MOORE, R. E.; PATTERSON, G. M. L.; TIUS, M. A.; J. Am. Chem. Soc. 116 (1994) 18, 8116-8125; Dep.

The siloxyenones (I) are coupled with the lithiated allene (II) to produce the carbinols (III) which are desilylated and subsequently epoxidized to give the oxiranes (IV).