Objective: Hypertension is a major non-communicable disease prevailing globally. This study was conducted to determine the effectiveness of laughter therapy on blood pressure among patients with hypertension at a selected hospital, in Kancheepuram District. Methods:A quantitative approach of pre-experimental one group pre-and post-test design was chosen for this study. A total of 50 samples were included in the study using purposive sampling technique. Pre-test was done using the structured instrument, and laughter therapy was implemented following which post-test was done for all the study group participants. Both descriptive and inferential statistics were used for analysis. Results:The distribution of demographic variables depicted that each 17 (34%) study participants were aged from 39-42 to 43-45 years, respectively. On the count of gender, male and female study participants were equal in numbers that is each 25 (50%). The distribution of level of blood pressure in pre-and post-test disclosed that all the 50 (100%) study group participants had Stage I systolic and diastolic hypertension in the pre-test whereas in post-test 45 (90%), had pre-hypertension systolic and diastolic, only 5 (10%) had Stage I systolic and diastolic hypertension. There was a statistically significant difference between pre-and post-test systolic and diastolic blood pressure within study group participants at level p<0.001. Conclusion:This study findings implied that laughter therapy was effective to sustain the blood pressure within the optimal level among patients with hypertension.