cute pulmonary embolism (PE) is a serious and life-threatening condition that affects about 1 to 2 in every 1,000 adults annually in Canada and the US. 1 It is the third leading cause of cardiovascular death after acute coronary syndrome and stroke. 2 The ambiguity and overlap of its presenting symptoms, such as tachycardia, dyspnea, chest pain, and syncope, make the diagnosis of PE a challenge. The mnemonic approach and treatment algorithm presented in this article will allow NPs to better manage PE by initiating appropriate and timely treatment. Current management of PE no longer requires lengthy hospital stays, if any, as treatment modalities have evolved to benefi t both the patient and the healthcare system. 1 2 to strong risk factors such as lower limb