Persistent social disparities in the adoption of distributed energy resources (DERs) have prompted calls for enabling more equitable uptake. However, there are indications that limits inherent to grid infrastructure may hinder DER adoption. In this study we analysed grid limits to new DER integration across California's two largest utility territories. We found that grid limits reduce access to solar photovoltaics to less than half of households served by these two utilities, and may hinder California's electric vehicle adoption and residential load electrification goals. We connected these results to demographic characteristics and found that grid limits also exacerbate existing inequities: households in increasingly Black-identifying and disadvantaged census block groups have disproportionately less access to new solar photovoltaic capacity based on circuit hosting capacity. Our results illuminate the need for equity goals to be an input in the design of policies for prioritizing grid upgrades.
Imiquimod cream 5% is an immune modifier approved for the treatment of genital warts, actinic keratosis, and basal cell carcinoma. This case report presents an isolated case of telogen effluvium after 6 weeks of imiquimod treatment for an actinic keratosis on the scalp. Based on this case presentation, telogen effluvium is a potential rare side effect from imiquimod treatment.
Imiquimod cream 5% is an immune modifier approved for the treatment of genital warts, actinic keratosis, and basal cell carcinoma. This case report presents an isolated case of telogen effluvium after 6 weeks of imiquimod treatment for an actinic keratosis on the scalp. Based on this case presentation, telogen effluvium is a potential rare side effect from imiquimod treatment.
Background The cellular immune system plays an important role in the pathogenesis of psoriasis. The digestive system (by virtue of the profile, number and species of bacteria present at any given time and nutritional factors) can influence the status of the immune system. Bacterial pathogens influence specific cytokine activity due to the activity of superantigens. Modulation of bacterial gut flora offers a potential target for psoriasis treatment. Methods Forty-two subjects with mild to moderate plaque-type psoriasis were enrolled in a 12-week, randomized, placebo-controlled trial of a lactobacillus nutritional supplement. The supplement or placebo was taken orally once daily for eight weeks. The primary outcome of this study was the change from baseline to week 12 (or end of treatment) in the composite score of the signs of psoriasis (erythema, scaling, plaque thickness) for target lesions. Other outcomes included Investigator's and Subject's Global Assessment of Response and change in pruritus score. Results Data were evaluable for 40 subjects (18 on the nutritional supplement and 22 on placebo). No significant improvement was found with the lactobacillus nutritional supplement compared to placebo-treated patients. Conclusion Patients commonly seek out alternative treatments for psoriasis. Nutritional supplementation is an intriguing way to manage the disease, offering the potential for a very safe treatment, however we found little to no benefit for lactobacillus nutritional supplement in this group of subjects with mild to moderate psoriasis.
Migrant farmworkers experience a high incidence of skin disease. This report provides information on the case history of cutaneous larva migrans in a Latino migrant farmworker. Treatment options are reviewed, and information for prevention is discussed.
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