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A simple handling box for rhesus monkeys is described. It is easy to use and there is minimal contact between handler and monkey, thereby ensuring greater safety for personnel working with these animals than is found with other methods of handling. For minor procedures there is no need to sedate monkeys restrained in the box. The box can easily be adapted for use with other primate species and for the performance of a wide variety of experimental techniques.

Immunization of nine rhesus monkeys with human chorionic somatomammotrophin (HCSM) consistently produced high-titre monospecific antisera that did not cross-react with the related antigen, human growth hormone (HGH). However, two monkeys immunized with HGH developed lower-titre antisera that cross-reacted with HCSM. By contrast, rabbits and goats did not discriminate to any great extent between HCSM and HGH.

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