1Z profiles followed a theoretical square-law functional dependence [4]. Our preliminary results show that R 2 CP is sensitive to hydration levels as well as the acyl position, thus indicating the presence of slow dynamic modes. The R 2 CP rates of the acyl segments near the polar head groups increase with lipid dehydration, while the acyl segments deeper in the hydrophobic region show lower R 2 CP values at high dehydration levels. Similar studies in presence of peptides and proteins can give insight into optimized lipid hydration for protein functionality and slow cooperative motions.