Avian influenza A(H7N9) virus (A(H7N9)) emerged in February 2013. Liver impairment of unknown cause is present in 29% of patients with A(H7N9) infection, some of whom experience severe liver injury. Hypoxic hepatitis (HH) is a type of acute severe liver injury characterized by an abrupt, massive increase in serum aminotransferases resulting from anoxic centrilobular necrosis of liver cells. In the intensive care unit (ICU), the prevalence of HH is ∼1%–2%. Here, we report a 1.8% (2/112) incidence of HH in the largest single-centre cohort of ICU patients with A(H7N9) infection. Both HH patients presented with multiple organ failure (MOF) involving respiratory, cardiac, circulatory and renal failure and had a history of chronic heart disease. On admission, severe liver impairment was found. Peak alanine aminotransferase (ALT) and aspartate aminotransferase (AST) values were 937 and 1281 U/L, and 3117 and 3029 U/L, respectively, in the two patients. Unfortunately, both patients died due to deterioration of MOF. A post-mortem biopsy in case 1 confirmed the presence of centrilobular necrosis of the liver, and real-time reverse transcription polymerase chain reaction of A(H7N9)-specific genes was negative, which excluded A(H7N9)-related hepatitis. The incidence of HH in A(H7N9) patients is similar to that in ICU patients with other aetiologies. It seems that patients with A(H7N9) infection and a history of chronic heart disease with a low left ventricular ejection fraction on admission are susceptible to HH, which presents as a marked elevation in ALT at the time of admission.

The vertical structural stability of floating drilled shaft during sinking is an important practical issue on the safety of boring technique in the deep and thick alluvium. In fact, the vertical structural stability of shaft lining is a matter of overturn buckling. Theoretical analysis shows that the height of balance water (HBW) is the most important factor for the vertical structural stability of shaft lining. If the HBW is controlled in a reasonable range, the shaft lining will not buckle during construction. The shaft lining is regarded as a slender bar with closed bottom and floating in the mud while sinking. According to the mechanical analysis on the shaft lining from floating and sinking to the process of contacting the well bottom, a reasonable range of the HBW is deduced. Finally, with practical instances, the author in this article introduces the calculation principle in vertical structural stability of shaft lining while sinking and floating using finite element method (FEM). The simulation results show that in the reasonable range of HBW, the stability of shaft lining increases as the height of balance water goes up.

This paper proposes a method based on Lossy Counting to mine frequent itemsets. Logarithmic tilted time window is adopted to emphasize the importance of recent data. Multilayer count queue framework is used to avoid the counter overflowing and query top-Kitemsets quickly using a index table.

Li (2018) Author Correction: Prevalence and characteristics of hypoxic hepatitis in the largest single-centre cohort of avian influenza A(H7N9) virus-infected patients with severe liver impairment in the intensive care unit,