When using single-end tensioned carbon-fiber reinforced polymer (CFRP) fabric to strengthen reinforced concrete (RC) columns, the contact length between CFRP fabric and column increases with the increase in column diameter, and the prestress losses are often very large at the distance farthest from the anchorage. To address the problem, a method for double-end transverse prestressing of CFRP fabric for strengthening large diameter RC columns is proposed in this paper. Tests were carried out on 20 RC column specimens strengthened with prestressed CFRP fabric in constant temperature and humidity. The prestress losses due to friction during the tensioning process