Abstract. In view of the problem happened nowadays that the deviation found in the selection of technical solution in the enterprise, on the basis of analyzing the characteristic, this article proposed the solution by technical and economic analysis method, introduced the procedure how to use this method in detail and verified by a case study of a manufacturing company for example. The results show that the application of technical and economic analysis method can provide a scientific basis for the enterprise to formulate and choose technology solutions, which means great significance for the enterprise to invest and make strategic decision.