No abstract

Purpose To explore cell death in blue light induced retinal damage.Methods Sprague-Dawley rats reared under cyclic light were exposed continuously to diffuse blue light (400-480 nm) at 0.64 W/m 2 for 3 or 6 h after 22 h of dark adaptation. The rats were kept in darkness and killed Conclusion Photoreceptor cell apoptosis is seen early after the retina is damaged by blue light.

PPP reduces IGF-1-dependent VEGF expression and CNV in vivo. Accordingly, IGF-1R inhibitors may be useful tools in the treatment of conditions associated with CNV, including neovascular AMD.

PPP reduces IGF-1 dependent VEGF expression and CNV in vivo. Accordingly, IGF-1R inhibitors may be useful tools in the therapy of conditions associated with CNV including neovascular AMD.