Abstract:The current report describes the development of a dual modality tomographic agent for both positron emission tomography and magnetic resonance imaging (PET/MRI). The dual-modality agent in this study was based on a 124 I (PET) radiolabeled tri-gadolinium endohedral metallofullerene Gd 3 N@C 80 (MRI) nanoprobe platform. The outer surface of the fullerene cage of the Gd 3 N@C 80 metallofullerenes was surface functionalized with carboxyl and hydroxyl groups (f-Gd 3 N@C 80 ) using previously developed procedures and subsequently iodinated with I-f-Gd 3 N@C 80 , which could ultimately be used for simultaneous PET/MR imaging.

Abstract:The performance of passively mode-locked Nd:GYSGG lasers was investigated for the first time. The 1061.5 nm continuous wave (CW) mode-locking operation of the Nd:GYSGG crystal was achieved and pulse as short as 3.1 ps have been generated with a semiconductor saturable absorber mirror (SESAM). At the pump power of 7.39 W, the maximum average output power of 1.27 W was obtained with the slope efficiency of 18.9%. The pulse repetition rate of 42 MHz was obtained.Intensity, ×10 4 a.u.

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