Porcine reproductive and respiratory syndrome (PRRS) is one of the most serious diseases affecting the swine industry worldwide; however, there is no efficient control strategies against PRRSV at present. Therefore, development of new antiviral treatment strategies is urgently needed. As reported, germacrone can efficiently impair influenza virus replication. In this study, we exploited whether germacrone has the potential to inhibit PRRSV infection. Our results showed that the germacrone significantly inhibited replication of PRRSV in vitro and repressed the synthesis of viral RNA and protein. However, it did not block PRRSV binding and entry. Further studies confirmed that germacrone impaired PRRSV replication at an early stage, and inhibited infection of both classic and highly pathogenic type II PRRSV strains. Collectively, our findings imply that the germacrone has the potential to be used as an anti-PRRSV drug.

The rapid developpment of industrialization and urbanization has caused extensive environmental pollution, especially water pollution. Here, a bud-like shaped CdS (cadmium sulfide), with O-CNTs (oxidized multiwalled carbon nanotubes) homogeneously embedde (BCO), were synthesized by a facile hydrothermal process. The surface properties of the composites and the photocatalytic performances were studied systematically. The photocatalytic degrading anionic dye Methyl orange (MO) and cationic dye Rhodamine B (RhB) under visible light (λ � 420 nm) unveiled that BCO nanocomposites exhibited much better photocatalytic decolorization activity than bud-like shaped CdS. Due to the delaying time of electron recombination to the hole and the participation of holes (h + ) and * superoxide radicals ( * O 2 À ) by loading O-CNTs, BCO-3 wt% could decolorize 98.5 % RhB in 30 min and 95.5 % MO in 90 min, implying potential applications prospect.

No abstract

1. A ultra-large surface area of porous graphitic biochar was successfully using corn starch and ZnCl2 by a one-step method. 2. The adsorption capacity of tetracycline on the biochar could get 1122.2 mg g−1 at room temperature.