BCL-XL protein is among the most important members of the anti-apoptotic subfamily of BCL-2 protein family, as currently a promising new target for anti-tumor drug research, even though BCL-XL/2 proteins...

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Structures of muscarinic acetylcholine receptors illustrate the strikingly high degree of homology of the residues among isoforms, thus leading to difficulty in achieving subtype selectivity when targeting these receptors and...

Adenosine A1 receptor (A1AR) and Adenosine A2A receptor (A2AAR) are AR isoforms that share highly homologous, but play many different roles in terms of regulating arteriolar pressure and urine flow...