PurposeThe popularity of massive open online courses (MOOCs) has attracted worldwide research interest. This study aims to identify and summarize the research foci (e.g. themes, methods, contexts, etc.) and discuss the new directions and trends of MOOC research in the context of Mainland China.Design/methodology/approachA systematic review of the published MOOC research papers in Mainland China was conducted with the following inclusion criteria: (1) papers written in English; (2) context focused on Mainland China; and (3) empirical studies. Three main issues were explored with the selected 70 papers: (1) research methods (data collection and analysis); (2) the research foci; and (3) research objects.FindingsThe results found that the major MOOC research in China was quantitative, mostly using one method to collect data. Most studies collected data through the databases of MOOC platforms and survey techniques, which was consistent with the widely used descriptive statistics for data analysis. Learner-focused themes were investigated the most, aligning with the result that learners were the most popular research objects.Practical implicationsThe findings suggest that using new technology tools, such as the Big Data approach for learning analytics, may transform traditional MOOC research into new practices. Transdisciplinary research concepts may also provide an alternative evolving model for constructing collaboratively dynamic research frameworks under the changing technologies and paradigms. Meanwhile, educational research traditions, such as qualitative methods, contribute to scaffolding MOOC research for more pragmatic applications.Originality/valueMost systematic reviews on MOOCs focus on general or regional contexts other than Mainland China, and scant MOOC review is based on published English papers about Mainland China.