With the continuous development of deep learning, the performance of the intelligent diagnosis system for ocular fundus diseases has been significantly improved, but during the system training process, problems like lack of fundus samples and uneven sample distribution (the number of disease samples is much smaller than the number of normal samples) have become increasingly prominent. In view of the previous issues, this paper proposes a method for generating fundus images based on “Combined GAN” (Com-GAN), which can generate both normal fundus images and fundus images with hard exudates, so that the sample distribution can be more even, while the fundus data are expanded. First, this paper uses existing images to train a Com-GAN, which consists of two subnetworks: im-WGAN and im-CGAN; then, it uses the trained model to generate fundus images, then performs qualitative and quantitative evaluation on the generated images, and adds the images to the original image set to expand the datasets; finally, based on this expanded training set, it trains the hard exudate detection system. The expanded datasets effectively improve the generalization ability of the system on the public datasets DIARETDB1 and e-ophtha EX, thereby verifying the effectiveness of the proposed method.

Spatial resolution is an important indicator that measures the quality of remote sensing images. Image texture has been successfully recovered by generative adversarial networks in deep learning super‐resolution (SR) methods. However, the existing methods are prone to image texture distortion. To solve the above problems, this paper proposes an improved generative adversarial network to enhance the super‐resolution reconstruction effect of medium‐ and low‐resolution (LR) remote sensing images. This network is based on the Super Resolution Generative Adversarial Network (SRGAN), which makes great improvements in the structure of the connection between the inside and outside of the residual block and the design of the model loss function. At the same time, the G1–G2–G3 structure between residuals effectively combines the image information of the three scales of small, medium and large. The model loss function can be designed based on the Charbonnier loss function to narrow the pixel distance between the reconstructed remote sensing image and the original image. Furthermore, targeted perceptual loss can direct the network to restore the texture details of the image according to the semantic category. The subjective and objective evaluation of the generated images and the ablation experiments prove that compared with SRGAN and other networks, our method can generate more realistic and reliable textures. Additionally, the indicators [peak signal‐to‐noise ratio (PSNR), structural similarity (SSIM), multiscale structural similarity (MS‐SSIM)] used to measure the quality of the reconstructed image obtain improved objective quantitative evaluation.