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Haemophilus parasuis is the causative agent of Glässer's disease, which is responsible for the increasing economic losses in the pig industry worldwide. In this study, selective capture of transcribed sequences approach was used to investigate the transcriptional responses of H. parasuis to iron-restriction stress. Thirty-six genes were identified to be up-regulated under iron-restricted conditions. Knowledge of the genes involved in adaptation to environments encountered during disease will help understand the mechanisms of pathogenesis for this economically significant bacterium.

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The cooperative and competitive (i.e., co-opetition) behavior between retailers plays a significant role in the development of operations and marketing strategies in a supply chain. Specifically, retailers’ co-opetition relationship pivotally influences the sustainable performance in a closed-loop supply chain. This study examines the impact of retailer co-opetition on pricing, collection decisions and coordination in a closed-loop supply chain with one manufacturer and two competing retailers. Based on observations in some industries (e.g., electronic manufacturing, fabric and textile, etc.), the cooperative and competitive relationships between retailers can be classified into the following three different modes: Bertrand competition, Stackelberg competition, and Collusion. In this paper, we establish a centralized and three decentralized game-theoretic models under these three co-opetition modes and characterize the corresponding equilibrium outcomes. The results indicate that the Bertrand competition mode yields the highest return rate, which is also superior to the other two modes for both the manufacturer and the supply chain system in terms of profitability. However, it can be shown that which mode benefits the retailers would depend on the degree of competition between the retailers and the relative remanufacturing efficiency. Interestingly, we find that the retailer’s first-move advantage does not necessarily lead to higher profits. In addition, we design a modified two-part tariff contract to coordinate the decentralized closed-loop supply chains under three different retailer co-opetition modes, and the results suggest that the optimal contractual parameters in the contracts highly rely on the remanufacturing efficiency and the competition degree between the two retailers. Several managerial insights for firms, consumers and policy makers are provided through numerical analysis.