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Au@PdAg core–shell nanotubes using the galvanic displacement reaction were prepared and they exhibited excellent electrocatalytic performance towards methanol electrooxidation.

Two orthogonal routes for preparing (S)-2-methylazetidine as a bench stable, crystalline (R)-(-)-CSA salt are presented. One route features the in situ generation and cyclization of a 1,3-bis-triflate to form the azetidine ring, while the second route involves chemoselective reduction of N-Boc azetidine-2-carboxylic acid. Both sequences afford the desired product in good overall yields (61% and 49%) and high enantiomeric excess (>99% ee), avoid column chromatography, and are suitable for the large-scale production of this material.

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Reductive Amination/Cyclization of ω-Trifluoromethyl Keto Esters to Trifluoromethylated δ-Amino Alcohols and Lactams. -A diversity of biologically interesting trifluoromethylated four-to seven-membered lactams (VIII) and (XII) is prepared using an imination-reduction-base-induced cyclization sequence starting from ω-trifluoromethyl keto esters (I) and (IX), respectively. Reduction of tautomeric imine-enamine mixtures (III) -(V) provides δ-trifluoromethyl δ-amino alcohols (VII) as main side products. -(WAN, W.; HOU, J.; JIANG, H.; YUAN, Z.; MA, G.; ZHAO, G.; HAO*, J.; Eur.