Hydrogenated naphthalene derivatives Hydrogenated naphthalene derivatives Q 1010Titanium-Mediated [2 + 2 + 2] Coupling of Diynes with Homoallylic Alcohols. -Isomerization-free coupling of diynes with homoallylic alcohols in the presence of a titanum alkoxide and a Grignard reagent is presented. Unlike titanium aryloxides, the titanium alkoxide-mediated cycloaddition requires the use of homoallylic alcohols as the olefin component. Alcohols (V), bearing longer tether than homoallylic alcohols, give lower yields of desired cycloadducts and additionally products derived from competitive 1,5-hydrogen shift. With secondary homoallylic alcohols, high 1,3-diastereoselectivity is observed. -(SUNG, M. J.; PANG, J.-H.; PARK, S.-B.; CHA*, J. K.;

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