Highlights Covered broad fields of ageing in China: statistics, basic and translational research, long-term care, policy and social networks. Provided more detailed numerical updates of the ageing challenges in China. New features of the aging-related challenges, e.g., oral ageing and STDs in the elderly in China. A new and independent section on immune ageing. We also mentioned the COVID-19-induced death in the Chinese elderly.

[1] Ionospheric origin O + accelerated in the cusp/cleft region convects over the polar cap and flows along open field lines to the tail lobes. Some O + in the lobes enters the nearEarth plasma sheet where it is then convected to the inner magnetosphere, while some O + ends up in the distant tail where it is lost. In order to understand the transport of ionospheric O + to the plasma sheet so as to understand its contribution to the formation of geomagnetic storms, we have determined the occurrence frequency of cusp source O + over the polar caps and in the lobes to determine where and when it is observed. The results show that the probability of observing O + along the transport path is high even during nonstorm times, although, as expected, the highest probability is found during storm times. It was also found that when interplanetary magnetic field (IMF) By is positive, O + from the northern cusp/cleft tends to stream toward the dawnside tail lobe while O + from the south are observed on the duskside. The transport path for negative IMF By is more symmetric, but shows some evidence for a reversed asymmetry when IMF By is strongly negative. IMF Bz has little influence on the asymmetry. The asymmetry for positive By and lack of mirror symmetry between positive and negative By most likely result from the combination of convection driven by the solar wind and coupling with the ionosphere. Similar asymmetries have been observed in the convection patterns over the polar caps, which are attributed to a day-night ionospheric conductivity gradient adding to the IMF By effect. However, there are some disagreements between the asymmetries observed in polar cap potential patterns and the asymmetries observed in the O + spatial distribution, indicating there may be other causes for the symmetry breaking, in addition to the day-night conductivity gradient.

Knowledge of the ion composition in the near-Earth's magnetosphere and plasma sheet is essential for the understanding of magnetospheric processes and instabilities. The presence of heavy ions of ionospheric origin in the magnetosphere, in particular oxygen (O + ), influences the plasma sheet bulk properties, current sheet (CS) thickness and its structure. It affects reconnection rates and the formation of Kelvin-Helmholtz instabilities. This has profound consequences for the global magnetospheric dynamics, including geomagnetic storms and substorm-like events. The formation and demise of the ring current and the radiation belts are also dependent on the presence of heavy ions. In this review we cover recent advances in observations and models of the circulation of heavy ions in the magne- tosphere, considering sources, transport, acceleration, bulk properties, and the influence on the magnetospheric dynamics. We identify important open questions and promising avenues for future research.

Objective To investigate the characteristics of epidemiological distribution of the ossification of the ligamentum flavum (OLF) in the thoracic spine including the incidence, segmental distribution, and shape. Methods Chest spiral computed tomography scans of 993 cases (male 506, female 487, mean age 60 years, range 5-102 years) who presented due to chest symptoms were analyzed with axial slices combined with sagittal slices. The conditions of OLF in the thoracic spine, including segments, thickness, location, and dural sac compression, were recorded. Prevalence was standardized according to the ''Age Structure of Population in Beijing 2008''. Results Among the population investigated, the standardized prevalence rate was 63.9 %. The standardized prevalence rate for males (68.5 %) was higher than that for females (59.0 %). The highest prevalence rate of OLF was in the 50-59 years age group (79.2 %); however, high density originated it can be found in individuals aged 10-19 years. The comparison of different thoracic segments showed that T10-11 (44.0 %) and T11-12 (41.6 %) had the highest prevalence rates. ConclusionThe prevalence of ossification of the ligamentum flavum was highest in the 50-59 years group, but also occurred in early years. OLF occurs more frequently in the lower than in the upper and middle thoracic regions and its prevalence increases with aging.

We examined whether between-persons differences and within-person changes in levels of social support were associated with age-related cognitive decline and whether these associations varied by sex and by relationship type. Executive function and memory scores over 8 years (2002–2010) were analyzed by mixture models among 10,241 adults aged ≥50 years in the English Longitudinal Study of Ageing. Between-persons differences and within-person changes in positive social support and negative social support were independently associated with cognitive decline in different ways according to sex and relationship type. Among men, higher-than-average positive social support from a spouse/partner was associated with slower cognitive decline (for executive function, βperson-mean×time-in-study = 0.005, 95% CI: 0.001, 0.010; for memory, βperson-mean×time-in-study = 0.006, 95% CI: 0.000, 0.012); whereas high negative social support from all relationship types was associated with accelerated decline in executive function (for all relationships combined, βperson-mean×time-in-study = −0.005, 95% CI: −0.008, −0.002). For women, higher-than-average positive social support from children (β = 0.037, 95% CI: 0.010, 0.064) and friends (β = 0.115, 95% CI: 0.081, 0.150)—but not from a spouse/partner (β = −0.034, 95% CI: −0.059, −0.009) or extended family (β = −0.035, 95% CI: −0.064, −0.006)—was associated with higher executive function. Associations between social support and age-related cognitive decline vary across different relationship types for men and women.