The Delphi method is also called an expert consultation method, scientifically measuring the objectivity, practicality, and authority of the metric. This study aims to build a standard plan for chronic disease management care services in hospitals and guide the development of chronic disease management care services. This article proposes a chronic disease management nursing experiment, further revises the current hospital chronic disease management nursing service, redesigns the program, compiles the chronic disease management hospital nursing standard list according to the new program, and uses expert suggestions to modify the standard program items. It adopts a preliminary expert inquiry table, submits Delphi expert inquiry, and constructs a chronic patient prevention strategy for clinical nursing practice to learn from the reference for guiding the actual specific situation of nursing, providing evidence basis and practice guidance. More than 40 initial standards were listed, which were reduced to 30 after revision. The importance of the indicators to different experts was 3.56 to 4.85 points. The coordination coefficient is 0.180~0.356. Finally, after discussion by all parties, more than 40 specific indicators including the size of the new standard have been determined, which provides a great theoretical basis for the establishment of a new type of hospital chronic disease management and nursing service standard in my country. Based on process reconstruction and the Delphi method determined by the hospital chronic disease management nursing service standards, clear normative and operability can provide basis for the development of chronic disease management nursing services.