A new CDT agent, Cin-OD-Cu, which could continuously enrich in the mitochondria of A2780 cancer cells for generated ˙OH by Fenton-like reaction and induced mitochondrial damage, cell death.

A triphenylphosphine coordinated Cu(I) complex of Fc-OD-Cu, was rationally constructed for chemodynamic therapy (CDT) of cancer. The complex was capable of generating highly toxic hydroxyl radical (·OH) via Fenton-like reaction...

Chemodynamic therapy (CDT), in which highly toxic hydroxyl radicals (•OH) could be triggered by Fenton or Fenton-like reaction to kill cancer cells, has been emerged recently. Compared to traditional CDT...