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Street systems are the backbone of cities. With global urbanization and economic development, street systems have undergone significant development along with the growth of cities. In this paper, the authors select three cities with varying sizes, histories, locations, and growth dynamics: Stockholm, Toronto, and Nanjing. We analyze topological structures of their public street systems based on GIS and complex network theory. Considering the planarity of street systems, we first calculate various topological measures, including α, β, and γ indices, and density. This is followed by comparing three centrality measures, i.e., degree, betweenness, and closeness in complex network theory. In this part, we investigate these characteristics of nodes and edges in a primal representation, and discuss their relations with urban growth mechanisms.

IntroductionConstipation is one of the most common gastrointestinal symptoms in postpartum mothers. The choice of treatments for postpartum constipation remains a challenging clinical problem. Chinese herbal medicine has become increasingly popular as an alternative therapy for constipation. This systematic review aims to evaluate the efficacy and safety of Chinese herbal medicine for postpartum constipation.Methods and analysisWe will search PubMed (1946 to present), EMBASE (1974 to present), Cochrane Central Register of Controlled Trials (all years), Web of Science (1900 to present), Chinese Biomedical Literatures Database (1978 to present), China National Knowledge Infrastructure (1979 to present) and WANFANG data (1998 to present) to identify any eligible study. No restriction will be put on the language, publication date or status of the study. The primary outcome will be the spontaneous bowel movement. Secondary outcomes will be stool consistency, quality of life, transit time, relief of constipation symptoms and adverse events. We will perform the meta-analysis when more than one trial examines the same intervention and outcomes with comparable methods in similar populations. If the heterogeneity is not significant statistically (p>0.10 or I2<50%), the fixed-effect model will be built to estimate the overall intervention effects. Otherwise, the random-effect model will be used to provide more conservative results.Ethics and disseminationNo ethical issues are foreseen because no primary data will be collected. The results will be published in a peer-reviewed scientific journal.PROSPERO registration numberCRD42018093741