Jinna Dai scite author profile

A fast and sensitive LC/Q-TOF MS method has been developed and successfully utilized to screen the active ingredients of a Chinese medical formula, Zhi-zi-chi decoction, for the first time. The results indicated that the 24 compounds identified in rat plasma were the potential active ingredients of Zhi-zi-chi decoction, which provided helpful chemical information for further pharmacology and active mechanism research on Zhi-zi-chi decoction and other traditional Chinese medicines.

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A sensitive liquid chromatography–mass spectrometry method for simultaneous determination of two active chromones from Saposhnikovia root in rat plasma and urine

Dai

Chen

Cheng

et al. 2008

Journal of Chromatography B

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Determination of nifedipine in human plasma and its use in bioequivalence study

Guo¹,

Dai²,

Qian³

et al. 2007

International Journal of Pharmaceutics

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A sensitive liquid chromatographic–mass spectrometric method for simultaneous quantification of six iridoid glycosides from Zhi-zi-chi Decoction in rat plasma and its application to a pharmacokinetic study

Dai

Zhao

et al. 2013

Journal of Pharmaceutical and Biomedical Analysis

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Jinna Dai

Identification of multiple constituents in the traditional Chinese medicine formula Zhi‐zi‐chi decoction and rat plasma after oral administration by liquid chromatography coupled to quadrupole time‐of‐flight tandem mass spectrometry

A sensitive liquid chromatography–mass spectrometry method for simultaneous determination of two active chromones from Saposhnikovia root in rat plasma and urine

Determination of nifedipine in human plasma and its use in bioequivalence study

A sensitive liquid chromatographic–mass spectrometric method for simultaneous quantification of six iridoid glycosides from Zhi-zi-chi Decoction in rat plasma and its application to a pharmacokinetic study

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