With extensive ancient karsts and abundant oil and gas resources, the Ordovician carbonate reservoirs in the Huanghua depression have broad prospects of exploration and development. The types, characteristics, distribution and controlling factors of karsts were investigated by means of the analysis of cores, thin slices, logging, seismic, and geochemical data in this study. The study reveals that the Ordovician carbonate reservoirs in the Huanghua depression falls into three main categories, pore type, pore-vug-fracture type and fracture type, of which, pore-vug-fracture reservoirs account for 62%. The epigenetic uniform karst mainly developed in the Late Ordovician to Early Carboniferous, while the differential karst developed in the Mesozoic. The uniform karstification mainly include chemical dissolution of the original carbonate rock, while the differential karstification not only include chemical dissolution but also hydraulic erosion and biochemical dissolution by organic acid. The burial karstification mainly involved the dissolution of the Ordovician reservoir by large amount of acidic fluids generated by the overlying Upper Paleozoic coal measure source rock while generating hydrocarbon. The dissolution caused by upwelling magmatic-tectonic hydrothermal fluids along faults also contributed to the formation of burial karst reservoirs. The sedimentation-diagenesis and paleogeomorphology-tectonic movement have certain control effects on the karstification of the Ordovician reservoirs in the Huanghua depression, determining the reservoir quality.