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The third plague pandemic originated from Yunnan Province, China in the middle of the 19th century. The last human plague epidemic in Yunnan occurred from 1986–2005. On June 6, 2016, a case of human plague was reported in the Xishuangbanna Prefecture, Yunnan. The patient suffered from primary septicemic plague after exposure to a dead house rat (Rattus flavipectus), which has been identified as the main plague reservoir in the local epizootic area. Moreover, a retrospective investigation identified another bubonic plague case in this area. Based on these data, human plague reemerged after a silent period of ten years. In this study, three molecular typing methods, including a clustered regularly interspaced short palindromic repeats (CRISPR) analysis, different region analysis (DFR), and multiple-locus variable number of tandem repeats analysis (MLVA), were used to illustrate the molecular characteristics of Yersinia pestis (Y. pestis) strains isolated in Yunnan. The DFR profiles of the strains isolated in Yunnan in 2016 were the same as the strains that had previously been isolated in this Rattus flavipectus plague focus. The c3 spacer present in the previously isolated strains was absent in the spacer arrays of the Ypc CRISPR loci of the strains isolated in 2016. The MLVA analysis using MLVA (14+12) showed that the strains isolated from the human plague case and host animal plague infection in 2016 in Yunnan displayed different molecular patterns than the strains that had previously been isolated from Yunnan and adjacent provinces.

Precise measurement of two-neutrino double beta decay (DBD) half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay. We report the measurement of DBD half-life of 136Xe using the PandaX-4T dual-phase Time Projection Chamber (TPC) with 3.7-tonne natural xenon and the first 94.9-day physics data release. The background model in the fiducial volume is well constrained in situ by events in the outer active region. With a 136Xe exposure of 15.5 kg-year, we establish the half-life as 2.27±0.03stat.±0.10syst.×1021 years. This is the first DBD half-life measurement with natural xenon and demonstrates the physics capability of a large-scale liquid xenon TPC in the field of rare event searches.

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The Green Technology Innovation Behavior (GTIB) of construction enterprises is crucial for promoting green development in the construction industry. In order to clarify the mechanism of action affecting the GTIB of construction enterprises, this paper considers the context of green development in the construction industry based on the vector autoregressive model and constructs a theoretical model of GTIB in construction enterprises. Time series data collected by the Chinese government (2000–2018) were used to analyze the mechanism of action of the factors influencing the GTIB of construction enterprises by EViews 10.0. The results of the paper showed the following: (1) direct government investment has the greatest impact on the GTIB of construction enterprises and has made a positive contribution; (2) the added value of Gross Domestic Product (GDP) of the construction industry has a relatively small impact on the GTIB of construction enterprises; (3) the role of environmental regulation on the GTIB of construction enterprises is non-linear. This paper further broadens the research to the factors influencing the GTIB of construction enterprises. Meanwhile, this paper provides a reference basis for local governments to formulate policies related to the GTIB of construction enterprises.