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In women who present with pelvic masses, ROMA performed very well in distinguishing between noncancer lesions and EOCs but the combined HE4 and CA125 test was more effective in predicting EOC types.

Methods Medical records of 620 cases of ovarian cancer from Rajiv Gandhi Cancer Institute and Research Centre Delhi during years 2012-2013 were screened.118 cases were selected as per the inclusion and exclusion criteria. The detailed data regarding patients' clinical history, tumor characteristics, therapy, and recurrence etc. were assembled from their clinical records. The statistical analyses were performed using IBM SPSS Statistics for Windows, Version 23.0. Results Mean and median ages at diagnosis were 49.1 and 50 (range 23-75) years respectively. The mean and median serum CA 125 levels were 1423 and 544 (range 5.5-12431) ng/ml.

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