The Dombrock null reported here is due to a single Phe62Ser mutation. The expression data confirmed that 62Ser is responsible for lack of cell surface Do, and protein modeling suggests the mutation disrupts important aromatic side chain interactions between Phe62 and His160. Production of an antibody to a high prevalence Dombrock antigen (anti-Gya) in this patient was consistent with complete absence of Dombrock/ART4 protein.

On two tasks measuring cognitive “boundaries,” the performance of seventy-two hypnotized subjects was compared to the performance of seventy-two wakened subjects. On a task measuring the “boundary” between visual sensations and auditory sensations, all subjects counted the visible pulses of a metronome on some trials, counted the audible pulses of a metronome on other trials, and then decided whether they had seen or heard each number of counted pulses. Hypnotized subjects confused the visible pulses and audible pulses, whereas wakened subjects maintained the “boundary” between visible sensations and audible sensations. On a task measuring the “boundary” between visual sensations and emotional sensations, all subjects imaged specific emotions while viewing pictures of surprised faces, and then decided whether they had seen a surprised or emotional or assimilated (surprised-emotional) expression on each face. Hypnotized subjects assimilated the visual expressions and emotional images, whereas wakened subjects maintained the “boundary” between emotional sensations and visual sensations.

Anti-Vel was completely or partially adsorbed by RESt. Caution should be used when interpreting cold agglutinins with this method. The manufacturer warns that uncommon alloantibodies may be adsorbed.