Objective: To test the hypothesis that short-and long-term celecoxib administration has no effect on orthodontic tooth movement. Materials and Methods: Male Wistar rats were submitted to short-(3 days) and long-term (14 days) celecoxib administration, while the respective control groups received equivolumetric saline intraperitoneal injections. The upper left first molars of all rats were moved mesially for 14 days by a fixed orthodontic appliance exerting 50 g force upon insertion. After the experimental period, tooth movement was quantified and tissues around the first molar were processed for tartrateresistant acid phosphatase (TRAP) histochemistry. The amount of tooth movement and the number of TRAP-positive cells on the alveolar bone surface were evaluated. Results: The amount of tooth movement was significantly reduced in rats submitted to short-and long-term celecoxib administration, while the number of osteoclasts on the alveolar bone did not differ between the four groups studied. Conclusions: The hypothesis is rejected. Although celecoxib administration did not affect the number of osteoclasts, the osteoclast activity might be reduced, which could explain the inhibition of tooth movement observed in the celecoxib-treated animals. These results indicate that orthodontists should be aware of patients under short-and long-term therapy with celecoxib.

ABSTRACT:The orthodontic documentation carried out in radiological clinics is essential for diagnosis, planning and control of the orthodontic treatment. Amongst the diagnosis elements used are the cephalometric measurements, and errors can be incorporated as they are obtained. The objective of this work was to evaluate the values of some cephalometric measurements obtained in three radiological clinics using 30 lateral cephalometric radiographs of the head randomly chosen from the archives of the Department of Child Dentistry (Discipline of Orthodontics), School of Dentistry of Piracicaba, UNICAMP. These values were compared with the measurements obtained manually (control group) using variance analysis and Tukey's and Friedman's tests. Of the fourteen cephalometric measurements evaluated, the results demonstrated that only four of them presented statistically significant differences: IMPA, 1-NA, FMA, and H-nose. We concluded that although the majority of the mean cephalometric values did not present statistically significant differences, a great variability in the results was found when all the radiographic values were compared. This variability may influence the interpretation of the cephalometric measurements. Hence, we suggest that when the practitioner receives orthodontic documentation, he/she should redo the cephalometric analysis and compare the measurement values found with those presented to him. In addition, the practitioner should be prepared to use other elements for diagnosis, planning and control of the orthodontic treatment. DESCRIPTORS: Cephalometry; Observation variations; Diagnostic errors. RESUMO:A documentação ortodôntica realizada em clínicas radiológicas é essencial para diagnóstico, planejamento e controle do tratamento ortodôntico. Dentre os elementos de diagnóstico utilizados estão as grandezas cefalométricas, e erros podem ser incorporados durante a obtenção das mesmas. O objetivo deste trabalho foi avaliar os valores de algumas grandezas cefalométricas obtidas em três clínicas radiológicas, utilizando-se 30 telerradiografias da cabeça em norma lateral, escolhidas ao acaso, do arquivo do Departamento de Clínica Infantil (Disciplina de Ortodontia) da Faculdade de Odontologia de Piracicaba -UNICAMP. Esses valores foram comparados com os das grandezas obtidas manualmente (grupo controle), utilizando-se a análise de variância e os testes de Tukey e Friedman. Os resultados demonstraram que das 14 medidas cefalométricas avaliadas, apenas 4 apresentaram diferenças estatisticamente significantes: IMPA, 1-NA, FMA, e H-nariz. Concluímos que apesar de a maioria dos valores médios das grandezas cefalométricas não apresentarem diferenças estatisticamente significantes, ao compararmos todos os valores obtidos em cada uma das radiografias, encontramos grande variabilidade nos resultados, o que pode interferir na interpretação das grandezas cefalométricas. Assim, os autores sugerem ao ortodontista, quando receber a documentação ortodôntica, realizar novamente as análises cefalométricas para comparar ...

Black individuals present craniofacial characteristics which differ from those of other races, especially the white race, whose cephalometric analyses are usually considered as the standard in routine orthodontic diagnosis and treatment planning. Further studies are therefore needed to enable more accurate and specific diagnoses for this ethnic group. The present study was conducted in order to assess average values for the nasolabial angle in young Brazilian black individuals with normal occlusion, and to assess the occurence of sexual dimorphism. Thirty-six lateral skull, extraoral radiographs from Brazilian black individuals were selected from the archives of the Scientific Recordings Department, Orthodontics Graduate Program, School of Dentistry of Piracicaba, State University of Campinas (UNICAMP). The patients' ages varied from 10 to 14 years, they presented normal occlusion upon clinical examination, and had not been submitted to orthodontic treatment. The cephalometric landmarks from which the nasolabial angle was obtained and measured were traced by a single researcher. Statistical analysis and evaluation of the results led to the conclusion that the nasolabial angle of young Brazilian black individuals is sharper, i.e., the soft tissue profile is more protruded. The average value for the whole sample was 88.14 o ± 12.52 o . The nasolabial angle was statistically smaller among females (p < 0.05), demonstrating the occurrence of sexual dimorphism. DESCRIPTORS: Cephalometry; Dental occlusion; Orthodontics; African continental ancestry group; Nasolabial angle. RESUMO:Os indivíduos melanodermas possuem características craniofaciais diferentes das apresentadas pelas demais raças, principalmente por leucodermas que, normalmente, são considerados como padrão nas análises cefalométricas utilizadas rotineiramente no diagnóstico e planejamento dos tratamentos ortodônticos. São, portanto, necessárias novas pesquisas que permitam um diagnóstico mais acurado e específico para esse grupo étnico. Os pesquisadores desenvolveram esta pesquisa com o objetivo de verificar valores médios do ângulo nasolabial em jovens melanodermas brasileiros com oclusão clinicamente normal e de verificar a ocorrência de dimorfismo sexual. Foram selecionadas 36 telerradiografias de cabeça, tomadas em norma lateral, de indivíduos brasileiros melanodermas, na faixa etária de 10 a 14 anos, de ambos os sexos, com oclusão clinicamente normal e que nunca se submeteram a tratamento ortodôntico, provenientes dos arquivos do Setor de Documentação Científica do Curso de Pós-Graduação em Ortodontia da Faculdade de Odontologia de Piracicaba da Universidade Estadual de Campinas. Sobre essas radiografias foram delimitados os pontos e as linhas que dão origem ao ângulo nasolabial, o qual foi traçado e medido por um único pesquisador. Após análise estatística e avaliação dos resultados, concluiu-se que o ângulo nasolabial em indivíduos jovens brasileiros melanodermas apresenta-se mais agudo, ou seja, o perfil tegumentar apresenta-se mais protrus...

Background: Sex determination by linear measurements of the bones is widely used because of the several kinds of death in which the corpses can be damaged. Aim: The aim of this study was to establish a logit for sexual dimorphism through measurements of the atlas vertebra. Settings and Design: The principle sample was composed of 191 skeletons belonging to the Forensic Physical Anthropology Laboratory Prof. Eduardo Daruge. However, first, a calibration with other 25 skeletons was carried out. Materials and Methods: Using a digital caliper, linear measurements were made of the anteroposterior diameter of the atlas vertebra (variable A), anteroposterior diameter of the rachidian canal (variable B), transverse diameter of the rachidian canal (variable C), and maximum transverse diameter of the atlas vertebra (variable D). Statistical Analysis Used: The data were analyzed using IBM ® SPSS ® 25 Statistics program. Results: The mean measurements of all four variables for men were higher than that for women, being observed that variable D obtained the major discrepancy between the sexes. Considering both sexes, the variable C obtained the best results of standard deviation, while the variable D achieved the worse results. The t -test observed acceptance about hypothesis that exists differences between the gender and all four measures assessed. The logit developed is sex = −24.970 + 0.183 × A + 0.230 × D, in which “A” represents anteroposterior diameter of the atlas and “D” represents the maximum transverse diameter of the atlas. Conclusion: This model results in 81.2% accuracy, 85.5% sensitivity, and 75.3% specificity.

Sturge-Weber syndrome is a congenital disorder characterized by vascular facial birthmarks and neurological abnormalities. Oral cavity involvement may occur, and the extent of the vascular abnormality may vary considerably. The present authors report the case of a 6-year-old girl with Sturge-Weber syndrome, focusing on the clinical and radiographic features. Her dental management involved a multidisciplinary team and included orthodontic treatment using removable appliances.