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In view of the challenges of the current coronavirus (COVID-19) pandemic and to protect both patients and ultrasound providers (physicians, sonographers, allied professionals), the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) has compiled the following expert-opinion-based guidance for the performance of ultrasound investigations in pregnancy and for gynecological indications. The guidance assumes that robust local processes are in place for cleaning ultrasound equipment after each patient routinely, and gives specific recommendations for ultrasound examinations in suspected or confirmed cases of COVID-19.