This manuscript has been reproduced from the microfilm master. UMI films the text directly from the original or copy submitted. Thus, some thesis and dissertation copies are in typewriter face, while others may be from any type of computer printer.The quality of this reproduction is dependent upon the quality of the copy submitted. Broken or indistinct print, colored or poor quality illustrations and photographs, print bleedthrough, substandard margins, and improper alignment can adversely affect reproduction.In the unlikely event that the author did not send UMI a complete manuscript and there are missing pages, these will be noted. Also, if unauthorized copyright material had to be removed, a note will indicate the deletion.Oversize materials (e-g., maps, drawings, charts) are reproduced by sectioning the original, beginning at the upper left-hand comer and continuing from left to right in equal sections with small overlaps. Each original is also photographed in one exposure and is included in reduced form at the back of the book.Photographs included in the original manuscript have been reproduced xerographically in this copy. Higher quality 6" x 9" black and white photographic prints are available for any photographs or illustrations appearing in this copy for an additional charge. Contad UMI directly to order. The author has granted a non-L'auteur a accorde m e licence non exclusive licence allowing the exclusive pennettant a la National Library of Canada to ~ibliothe~ue nationale du Canada de reproduce, loan, distribute or sell reproduire, preter, distribuer ou copies of this thesis in microform, vendre des copies de cette these sous paper or electronic formats. la forme de microfiche/film, de reproduction sur papier ou sur format Bectronique.The author retains ownership of the L'auteur conserve la propriete du copyright in this thesis. Neither the droit d'auteur qui protege cette these. thesis nor substantial extracts f?om it Ni la these ni des extraits substantiels may be printed or otherwise de celle-ci ne doivent Etre imprimes reproduced without the author's ou autrement reproduits sans son permission.autorisation. AbstractThis thesis examined the effect of skin type and cooling rate on the intensity, quality and timecourse of cold-evoked pain in normal human subjects.Cold stimuii were delivered to the thenar eminence (glabrous skin) and the dorso-lateral hand (hrury skin) via a 9cm2 Peltier-type stimulator. Cold and pain thresholds were determined by the method of Limits. A computerized visual analogue scale was used to obtain continuous ratings of pain intensity and affect. The McGill Pain Questionnaire was used to assess the quality of cold-evoked pain.Supra-threshold stimuli (34°C base) were delivered at 0.5, 1 or 2"C/s to 2"C, held for 20s and returned to baseline at g°C/s.These studies revealed: (1) Cold and cold-induced pain thresholds were lower (e.g. occurred at a higher temperature) for hairy compared to glabrous skin. (2) Power function exponents for suprathreshold ratings were larger for gl...