Employing a national sample of 1,162 employees, we examined the relationship between joh and career attitudes and the presence of a mentor, the mentor's type (formal or informal), the quality ofthe mentoring relationship, and the perceived effectiveness and design of a formal mentoring program. Satisfaction with a mentoring relationship had a stronger impact on attitudes than the presence of a mentor, whether the relationship was formal or informal, or the design of a formal mentoring program.
These studies suggest that the initial antiviral response to telaprevir is due to a sharp reduction in wild-type virus, which uncovers pre-existing telaprevir-resistant variants. In patients given telaprevir alone, viral rebound can result from the selection of variants with greater fitness. However, the combination of telaprevir and PEG-IFN-alpha-2a inhibited both wild-type and resistant variants. In the present study, every patient who began PEG-IFN-alpha-2a and ribavirin after the 14-day dosing period had undetectable HCV RNA levels at 24 weeks, indicating that telaprevir-resistant variants are sensitive to PEG-IFN-alpha-2a and ribavirin.
This study examines practitioners' compliance and noncompliance with risk/needs assessment tools, using a national survey of frontline community corrections staff. Focusing on respondents required to complete tools and make decisions based on them, analysis showed that tools were mostly filled out when required, but decisions were not always based on the tool result. latent class analysis suggests about half of the tool-using subgroup were "substantive" compliers who completed tools carefully and honestly and tended to use them for decision making. The remaining tool users were "formal" in their compliance: filling out the tools, but often making decisions that did not correspond with tool results, and in some cases even manipulating the information included in them. Multivariate analysis suggests that practitioners' belief in risk/needs tools, agency monitoring and training, perceptions of agency procedural justice, and agencies' projected confidence in their local risk/need tool may help explain patterns of compliance and noncompliance.
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