We compared PCR results from SARS-CoV-2-positive patients tested in the community in France from 14 June to 30 July 2021. In asymptomatic individuals, Cq values were significantly higher in fully vaccinated than non-fully vaccinated individuals (effect size: 1.7; 95% CI: 1–2.3; p < 10−6). In symptomatic individuals and controlling for time since symptoms, the difference vanished (p = 0.26). Infections with the Delta variant had lower Cq values at symptom onset than with Alpha (effect size: −3.32; 95% CI: −4.38 to −2.25; p < 10−6).
SARS-CoV-2 viral dynamics in infections with Alpha and Beta variants of concern in the French communityWe read with interest the article by Tang et al. on the multiple introductions of variant B.1.351 into the UK. 1 As SARS-CoV-2 variants of concern rapidly spread internationally, it is important to
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