Raw polysaccharides, previously described in detail, were isolated from the flowers of Hibiscus sabdariffa L. and fractionated by ion exchange chromatography into one neutral and three acidic subfractions. Raw polysaccharides and all acidic subfractions caused a strong induction of proliferation of human keratinocytes (HaCaT) of up to 40 %, while the neutral polymers were ineffective. While mitochondrial activity was not influenced, raw polysaccharides induced early differentiation of primary natural human keratinocytes, as determined by involucrin formation.
In fiber suspensions with low optical contrast, the in-situ characterization of structural properties with conventional microscopy methods fails. However, overlaying subsequent images of multiple particle tracking (MPT) videos including short...
Knowledge concerning passive mechanic cardiac properties is necessary to model behavior of whole hearts. Commonly, a continuum mechanics based description is chosen in conjunction with the finite element method. The aim of this work is to summarize, derive and evaluate hyperelastic material laws for inhomogeneous, anisotropic myocardium. Hence, different material laws were set up and their parameters were determined taking measurement data in literature into account. The material laws were compared from a theoretical and numerical point of view. Furthermore, the application of continuum mechanics based methods is evaluated concerning aspects of numerical solution and spatial discretisation. In further work the laws will be implemented and integrated in an existing software environment, which allows the calculation of deformations in complex geometries.
A reliable temperature measurement System working inside a MRI-system is required in order to determine the amount of local temperature rise during application of radiofrequency fields on medical implants and thus to ensure patient safety. Hence the aim of this study was to develop a cost-effective temperature measurement System suitablefor use in a MRI System to investigate this heating having mainly phantom experiments in mind. Three active temperature measurement Systems were set up, the first using a PTC äs the temperature sensor, the other two with platinum resistors of100 and 1000 . Interference tests in a MRI Systems were performed. It could be shown that a stable temperature measurement at a resolution ofO.l °C could be established.
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