Vestibular rehabilitation therapy plays an important preventive role in reducing falls in at-risk elderly patients, with beneficial effects seen at termination of therapy.
Vibration provided no additional benefit in initial treatment success or in reducing long-term relapse rates when included in the canalith repositioning maneuver. Many patients with benign paroxysmal positional vertigo require more than one canalith repositioning cycle at the time of initial treatment to relieve symptoms, but this does not indicate a higher likelihood for recurrence. No variable predicted a higher rate of recurrence.
We present a comprehensive, human genome-wide survey of disease-associated gene expression that extends the public database and provides new evidence for molecular mechanisms involved in cholesteatoma pathology. Laryngoscope, 123:S1-S21, 2013.
Amphiregulin is overexpressed in epithelial tissues of human cholesteatoma. Significant relationships were identified between increased amphiregulin expression levels and the extent of cholesteatoma migration and bone erosion. Our study results indicate amphiregulin is a potential biomarker of early cholesteatoma disease processes.
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