An environmentally benign, one-pot, A3-coupling reaction of various aldehydes, amines and terminal alkynes for the synthesis of propargylamine was catalysed by Amberlyst A-21 supported CuI, under heterogeneous and solvent-free conditions.

CuI supported on Amberlyst A-21 is shown to be a highly efficient heterogeneous catalyst for the three-component coupling of amines with various aliphatic or aromatic aldehydes and terminal alkynes leading to propargylamines. The catalyst can be reused several times without significant loss of activity. -(BOSICA*, G.; GABARRETTA, J.; RSC Adv. 5 (2015) 57, 46074-46087, http://dx.doi.org/10.1039/C5RA05546F ; Dep. Chem., Univ. Malta, 2080 Msida, Malta; Eng.) -Toeppel 38-054