A long-acting sulfanilamide, 2-methoxy-4-suIfanilamidoquinazoline (III), was prepared1 in low yield from 2,4-dimethoxyquinazoIine (I) and sodium sulfanilamide (II) using 2-methoxy ethanol as the reaction
Acknowledgment.-We are indebted to Mr. Osborne P. Crews, Jr., and his staff for the large-scale preparation of intermediates and to Dr. Peter Lim and his staff for the spectra and paper chromatography.
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