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Materials 11 Organisms Media Instruments and reagents General Methods Cultures Thin-layer chromatography Column chromatography Extraction and Purification of Prodigiosin 15 Extraction and Purification of Norprodigiosin 17 Attempts to Obtain Norprodigiosin Derivatives Benzoyl derivative 36 p-Nitrobenzoyl derivative 41 Zinc complex 42 Perchlorate of norprodigiosin 42 Trimethylsilyl derivatives of norprodigiosin 45 2,4-Dinitrophenylhydrazone 46 pK Determination of Norprodigiosin, Prodigiosin and Prodigiosin Analogs 46 Oxidative Degradation of Prodigiosin Norprodigiosin and Labelled Norprodigiosin 62 Oxidative degradation of norprodigiosin 64 Oxidative degradation of labelled norprodigiosin 64

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