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The aim of this article is to report a case of Aspergillus chorioretinitis successfully treated with intravitreal voriconazole based on an interventional case report. An immunodeficient patient, 34 years old, receiving systemic antifungal treatment for 1 month for invasive aspergillosis with necrotizing pneumonia and brain metastasis, who presented with blurred vision in his left eye. Visual acuity (VA) was 20/20 in his right eye, and 8/20 in his left eye. Ophthalmological examination showed a paramacular nodular yellowish chorioretinal lesion with intraretinal hemorrhages, in the absence of vitritis or anterior uveitis. The patient was treated with one dose of intravitreal voriconazole (100 μg/0.1 ml). One week after the intravitreal injection, the patient's VA was 10/20, the retinal lesions had diminished, and the hemorrhages had disappeared. At 3-month follow-up, his AV was 20/20 with a residual retinal scar. The significant and rapid improvement in this patient suggests that early injection of intravitreal voriconazole may be the first therapeutic option in Aspergillus chorioretinitis, obviating the need for vitrectomy.

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Purpose To evaluate the efficacy of a new technique for diode laser cyclophotocoagulation in refractory glaucoma. Methods A consecutive case series of 8 eyes of 7 Caucasian patients who underwent gonioprism assisted diode laser cyclophotocoagulation (GADC). GADC with a peripheral corneal approach is a new surgical technique that employs a manual gonioprism, iris hooks, ophthalmic operating microscope and an 810 nm laser diode probe usually utilized for retinal photocoagulation Results The mean follow‐up time was 5.9 months (range 3 to 11 months). Mean intraocular pressure (IOP) (±SD) was reduced from 24.5±4.3 mmHg to 11.25±1.7 mmHg. The mean number of IOP lowering eye drops (±SD) was reduced from 2.0±0.8 preoperatively to 0.8±0.5 postoperatively. The visual acuity remained unchanged in 7 of 8 eyes (87.5%) and deteriorated in 1 of 8 eyes (12.5%). Early complications included IOP spike in one patient. No major complications were encountered. No eyes required repeat cyclophotocoagulation. Conclusion Gonioprism assisted diode laser cyclophotocoagulation with peripheral corneal approach appears to be an effective and safe surgical treatment of refractory glaucoma and has the advantage of no requiring of new endoscopic devices.

<p>Artificial nourishment of sandy beaches using sediment from borrow areas located on the continental shelf is increasingly a recommended solution for reversing the erosion process that affects the coastal zone. However, the impact of sand extraction in the shelf and deposition on the beach on the benthic communities (structure and functioning) is still poorly known, contributing to the lack of information needed for the assessment of Descriptor 6 (Sea-floor integrity) of the Marine Strategy Framework Directive (MSFD).</p><p>The aim of this work is to evaluate the morphological and ecosystem impacts of sand extraction at the inner shelf, as well as the consequent impacts of sand deposition at the nourished beaches. In this context, short-term and long-term monitoring activities based on a multidisciplinary approach were implemented at new and former borrow areas located in the southern Portugal (Algarve) inner continental shelf and adjacent beaches. These activities include multibeam bathymetric surveys complemented by surface sediment sampling, wave and current measurements, and a fluorescent tracer-marked sand experiment. Moreover, benthic macrofauna composition and structure are being studied at borrow areas (former and new) and at the nourished beaches. The acquired data allow a first assessment of the recovery rates regarding the sea-bottom morphology and benthic communities, and contribute to a better understanding of the involved processes.</p><p>The authors would like to acknowledge the financial support FCT through project UIDB/50019/2020 – IDL and ECOEXA project (MAR-01.04.02-FEAMP-0016)</p>