Fused pyridine derivativesFused pyridine derivatives R 0450 Novel Analogues of 3-Substituted-2,3-dihydro-1,4-dioxino[2,3-b]pyridines: Modifications in the Dioxane Ring. -The synthesis of a series of novel analogues (IV), (VIII), (XI) and (XVI) of the 3-substituted-2,3-dihydro-1,4-dioxino[2,3-b]pyridine core modified in the non-aromatic ring, attractive intermediates for the preparation of potential new therapeutic agents, is presented. -(BARTOLOMEA*, J. M.; ALCAZAR, J.; ANDRES, J. I.; DE BRUYN, M.; FERNANDEZ, J.; MATESANZ, E.; VAN EMELEN, K.; Tetrahedron Lett. 44 (2003) 47, 8545-8548; Dep. Med. Chem., Johnson & Johnson Pharm. Res. Dev., E-45007 Toledo, Spain; Eng.) -D. Singer 09-124

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