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This is a retrospective and all‐inclusive study of ovarian histology of 74 patients who had therapeutic oophorectomy for advanced breast cancer at the Ellis Fischel State Cancer Hospital (1940‐1967). Results of the pathologic findings were itemized, coded, and correlated with all the clinical characteristics recorded. Our results showed that patients who had ovarian metastasis had higher rates of objective response than those who did not (36% vs. 11%, p = 0.02). In addition, patients with ovarian metastasis had a longer disease‐free interval and better survival after their initial mastectomy operations. However, our series is too small to show statistical significance. The coexistence of corpus luteum improved the response rates. In fact, a larger proportion of ovaries with corpus luteum contained metastasis (37% vs. 20%). Survival of patients whose ovaries had corpus luteum was much better at the fourth and fifth years after mastectomy (p = 0.03).

Carcinomatous involvement of the liver mimicking cirrhosis is a rare complication of metastatic carcinoma, most frequently seen with scirrhous carcinoma of the breast. The case of a 46‐year‐old woman with breast carcinoma presenting with ascites, jaundice, spider angiomata, and portal hypertension is reported. On hepatic scan the liver appeared to be almost the same size as the spleen, a finding frequently seen in cirrhosis. A chemotherapeutic program was introduced, but was of no benefit, and the patient died with uncontrolled esophageal bleeding. The prominent histologic feature on autopsy was intense stromal fibrosis and intravascular tumor infiltration with compression of vessels of the portal system.