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The evaluation of this surveillance tool resulted in objective and comparable data, which were adequate for a screening test. It is easily applicable as a screening tool, even though it was originally designed as a surveillance tool. The inclusion of risk factors to the scoring system is an innovation that allows for the identification of children with suspected delay in addition to developmental milestones, although the definition of parameters and choice of indicators should be thoroughly studied.

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Interest in hydrogen as a transportation fuel is growing. Fuel cell electric vehicles fed by hydrogen are expected to play a key role in the decarbonization of the transportation sector. Its impact will depend upon the existence of reliable and cost-effective fuelling stations. Numerical simulation allows sizing hydrogen refuelling on-site stations in order to identify the most cost-effective solution for a specific utilization pattern. This study aims to define a numerical optimization model for a hydrogen refuelling station to supply both light and heavy vehicles. The objective function is to minimize the total storage volume, taking into account the number of vehicles to be refuelled. The pressure at each storage skid is considered a decision variable, as well as the hydrogen mass that is provided at each vehicle filling. The model considers the hydrogen properties and the physical constraints to size the station prior to its construction. Additionally, a cost analysis based on the capital expenditure concept was developed. The hydrogen refuelling station must be able to supply 300 kg/day of hydrogen. The station includes four main systems: the hydrogen production equipment, an electrolyzer, and a system that can store hydrogen to feed the compression cascade. The station should be able to fill 10 heavy vehicles at 350 bar (H35), considering 2 skid pressure levels and a supplied mass of 30 kg and 30 light vehicles at 700 bar (H70), considering 3 skid pressure levels, dispensing 4.2 kg of hydrogen each. At all vehicle fillings, a pressure differential of 50 bar between the high-pressure skid and the vehicle tank is mandatory so the refuelling can be validated. The results show that it is possible to refuel 10 heavy vehicles considering a total storage volume of 36.9 m 3 , whereas, for light vehicles, it is possible to refuel 30 vehicles with a total volume of 22.9 m 3 . Based on capital expenditure, the most representative capital costs are the production equipment (30%), high-pressure storage unit (20%) and the hydrogen compression system (18%).

Background: Reports on pulmonary lipid deposition after parenteral nutrition (PN) in children were based on small samples. Here we report the prevalence of pulmonary lipid deposition in 114 consecutive autopsied children from a pediatric intensive care unit, including neonates, lactants, preschool, school children and adolescents that used or not PN before death. The objective of this study is to evaluate whether there is an association between the intrapulmonary deposition of fat and the use of lipid infusion in total parenteral nutrition in children.