HighlightsLeft-sided Gallbladders are considered a rare anatomic anomaly, even though, prevalence is increasing.This can be an incidental finding during surgery.It is in part due to the fact that radiographic images tipically do not detect them.Due to this, surgeons must be aware of this anomaly during surgery.

We have established and characterized a new ovarian cancer cell line derived from stage IV serous ovarian adenocarcinoma metastatic tissue from a 47 year old Ashkenazi Jewish patient. The patient developed ovarian cancer at age 44 and died of the disease at age 48. The tissue was obtained after an extensive secondary cytoreductive intraperitoneal surgery. Prior to the surgery the patient underwent primary cytoreduction followed by several systemic therapies with recurrences. A culture of the metastatic tissue was transfected with Simian Virus 40 Large T-Antigen and telomerase. The cell line has been in culture on and off during 3 years. The identity of the cell line was confirmed by Short Tandem Repeat genotyping on genomic DNA extracted from early and late passages as well as from frozen metastatic tissue. The cell line was further characterized by array-Comparative Genomic Hybridization and gene expression microarray; and by Spectral Karyotyping and Fluorescent In Situ Hybridization. The results of these analyses were compared, when appropriate, with those of frozen metastatic tissue. A low level of genetic instability was detected in the cell line, but the karyotypes seem to be near diploid and relatively stable, after several years of cultivation. We believe that this novel ovarian cancer cell line could contribute to the understanding of the molecular genetic basis of the disease in this advanced stage, and be representative of the tumors of a great number of patients that become resistant to the majority if not all known cancer therapies. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 3265.

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middle hepatectomy (n=2), and right trisectionectomy (n=1) or extended left hepatectomy (n=1) with IVC resection and reconstruction. Two patients experienced PMC (Clavien-Dindo classification IIIa: n=1, IIIb: n=1). There was no in-hospital mortality. Six patients are currently alive without recurrence with a median followup of 24 months. PTT [median (range)] in the TB group was significantly shorter: 19 (13-45) compared to 52 (18-174) min in the basic group (p=0.012). There was no significant difference in terms of EBL (p=0.918) and PMC (p=0.771). Conclusions: TB with the Pringle maneuver and infrahepatic IVC clamping is feasible and may offer rapidity during high complexity major LR.