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Two sisters with thyroid hemiagenesis are described. The patients presented diffuse thyroid enlargement of right lobe. The left lobe and isthmus were absent and thyroid scans were similar in both cases. The patients were clinically euthyroid. Basal serum thyroid hormones and TSH were within normal range, but TSH response to TRH administration was exaggerated in both patients. The finding of familial occurrence and the same functional and morphological characteristics of remnant thyroid tissue in both cases suggest a genetic determination for this abnormality.

The Roses granodiorite is a Variscan stock with well developed syn- and post-magmatic deformation structures that crops out in the Pyrenean Axial Zone. Analysis of structures reveals a continuous deformation history during and after magma cooling. The deformation history is divided on the basis of mechanical behaviour into two stages: an early one with the development of magmatic structures and a late stage with the development of mylonitic fabrics along shear zones. Both stages are separated in time by the emplacement of aplite-pegmatite dykes. Time of dyke emplacement is thought to coincide with a sudden change in rheology of the granodiorite. The abundance of quartz dioritic enclaves permits the use of shape analysis to characterize the magmatic fabric as a homogeneous deformation. Later solid-state deformation led to the development of an inhomogeneous deformation pattern with different sizes of anastomosing shear zones wrapping around lozenge-shaped domains. The displacement/width ratio measured in shear zones ranges between one and two orders of magnitude. The Roses granodiorite is thought to be a synkinematically emplaced stock which records a continuous deformatioinal history with two distinct deformation stages, both recording bulk finite strains of similar order of magnitude but with a marked difference in finite strain distribution.

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