Almost invariably, patients with NMDAr encephalitis had abnormal EEG. The presence of EDB, which can follow a pattern of well-characterized electroclinical seizures, in our patients was associated with seizures and SE. These findings suggest that EDB could be an evolutive pattern of an SE in NMDAr encephalitis. This article is part of a Special Issue entitled "Status Epilepticus".

The effect of music-supported therapy (MST) as a tool to restore hemiparesis of the upper extremity after a stroke has not been appropriately contrasted with conventional therapy. The aim of this trial was to test the effectiveness of adding MST to a standard rehabilitation program in subacute stroke patients. A randomized controlled trial was conducted in which patients were randomized to MST or conventional therapy in addition to the rehabilitation program. The intensity and duration of the interventions were equated in both groups. Before and after 4 weeks of treatment, motor and cognitive functions, mood, and quality of life (QoL) of participants were evaluated. A follow-up at 3 months was conducted to examine the retention of motor gains. Both groups significantly improved their motor function, and no differences between groups were found. The only difference between groups was observed in the language domain for QoL. Importantly, an association was encountered between the capacity to experience pleasure from music activities and the motor improvement in the MST group. MST as an add-on treatment showed no superiority to conventional therapies for motor recovery. Importantly, patient's intrinsic motivation to engage in musical activities was associated with better motor improvement.

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Infection is one of the most devastating complications of total knee arthroplasty. It is also the leading cause of early revision after knee arthroplasty, ahead of instability and aseptic loosening [ ].Treatment of an infected total knee arthroplasty requires to times more hospital resources than a primary arthroplasty and times more than an aseptic revision [ ]. The goal of treatment is to eradicate infection and maintain joint function. Two-stage exchange remains the treatment of choice in cases of late infection, with good or excellent results in % to % of cases nevertheless, it is aggressive, costly, and long. It is also considered the treatment of choice in cases of fungal infection, infection by virulent organisms, inflammatory diseases, immunosuppression, and reinfection after reimplantation.Compared with direct replacement, -stage revision of infected arthroplasty has several disadvantages longer hospital stay, higher cost, longer surgical time, tissue retraction, instability, and functional limitation between procedures. From a technical standpoint, surgical reimplantation may be hampered by retraction of soft tissue and loss of tissue planes.Most authors agree that almost all of these problems can be minimized using antibiotic-loaded articulating cement spacers, although -stage exchange can be used to eradicate infection both with and without cement spacers.