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Substituting bedaquiline for SLIs in MDR-TB treatment resulted in improved outcomes at 12 months compared with patients who remained on SLIs, supporting the use of bedaquiline for MDR-TB treatment in programmatic settings.

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Abstract.This paper gives a proof of Lie's second fundamental theorem in the context of infinite dimensional Lie groups; that is, we define a class of Lie subalgebras of the Lie algebra of a large class of infinite dimensional Lie groups, say G, which can be realized as the Lie algebras of Lie subgroups of G .